Slapped Cheek Syndrome

Also known as: Fifth Disease, Red Cheek Rash Virus, Slapped Face Rash, Childhood Red Cheek Virus, Fifth Disease Rash, Bright Red Cheek Illness

Last Updated: October 31, 2026

Key Points

Common in children, usually resolves in 3 weeks
Rarer in adults, can be more serious
Caused by parvovirus B19
Spread before the rash appears
Often managed with self-care at home

Overview

Slapped cheek syndrome, also known as fifth disease, is a common viral infection primarily affecting children. It is caused by the parvovirus B19 and typically resolves on its own within a few weeks. While less common in adults, the infection can sometimes lead to more serious complications. The virus spreads through respiratory droplets from coughs and sneezes, or by touching contaminated surfaces. People are most contagious before the characteristic rash appears, making it difficult to prevent spread. Once the rash develops, the person is generally no longer contagious. Most cases of slapped cheek syndrome do not require medical intervention and can be managed with home care to relieve symptoms. However, certain individuals, such as pregnant women or those with weakened immune systems, should seek medical advice.

Signs and Symptoms

Feeling unwell for a few days
High temperature
Runny nose
Sore throat
Headache
Bright red rash on cheeks
Lacy rash on body, arms, and legs
Joint pain and stiffness (common in adults)
Extreme tiredness (sign of severe anaemia)
Very pale skin (sign of severe anaemia)
Shortness of breath (sign of severe anaemia)
Fainting (sign of severe anaemia)

Things That Increase the Risk

Being pregnant (risk of miscarriage or complications)
Having a blood disorder (e.g., sickle cell disease, thalassaemia)
Having a weakened immune system (e.g., chemotherapy, HIV, diabetes)
Close contact with an infected person

Diagnosis

Based on typical symptoms and rash
Physical examination by a doctor
Blood tests (for at-risk groups or suspected complications)

Treatment & Management

Drink plenty of fluids to avoid dehydration
Continue normal feeding for babies
Take paracetamol for discomfort
Take ibuprofen for discomfort
Avoid aspirin for children under 16
Monitor for signs of severe anaemia
Seek medical advice if pregnant or immunocompromised

Prevention

Wash hands frequently with soap and water
Use tissues to cover coughs and sneezes
Dispose of used tissues quickly
Inform school or teacher if child has the syndrome
Avoid close contact with vulnerable individuals when unwell

Available Treatments

Explore our range of treatment options for Slapped Cheek Syndrome: