Low White Blood Cell Count

Also known as: Low WBC Count, Weakened Immune Cell Count, Low Infection-Fighting Cells, Reduced White Blood Cells, Low Immune Cell Levels, Depleted White Blood Cells

Last Updated: October 31, 2026

Key Points

Body not making enough white blood cells
Increases risk of infections
Can be caused by treatments or illnesses
Often has no symptoms initially
Diagnosed with a blood test

Overview

A low white blood cell count means your body isn't producing enough white blood cells, which are crucial for fighting off infections. This condition, also known as leukopenia, makes you more vulnerable to getting sick. It can be caused by various factors, including cancer treatments like chemotherapy and radiotherapy, certain medications (e.g., antipsychotics, overactive thyroid medicine), some cancers (like leukaemia), and infections such as HIV or hepatitis. Autoimmune conditions like rheumatoid arthritis can also lead to it. Treatment focuses on addressing the underlying cause and preventing infections. This often involves antibiotics, adjusting medications, or specific therapies to boost white blood cell production. Taking precautions to avoid infections is also very important.

Signs and Symptoms

Frequent infections
High temperature or chills
Sore throat
Recurring mouth sores
Toothache
Skin rashes
Tiredness
Flu-like symptoms

Things That Increase the Risk

Cancer treatment (chemotherapy, radiotherapy)
Certain medications (antipsychotics, thyroid medicine)
Some cancers (leukaemia)
Infections (HIV, hepatitis)
Autoimmune conditions (rheumatoid arthritis)

Diagnosis

Blood test
Doctor consultation for symptoms
Review of medical history and medications

Treatment & Management

Treating the underlying cause
Antibiotics for infections
Adjusting or stopping certain medications
Specific treatments to boost white blood cells
Managing existing infections
Monitoring for sepsis

Prevention

Avoid close contact with sick people
Proper food storage and preparation
Regular hand washing
Use an electric shaver
Avoid shared hot tubs
Do not share personal items (food, cups, toothbrushes)
Avoid raw foods (meat, shellfish, eggs)
Do not handle animal waste (cat litter, animal poo)
Do not change nappies
Avoid walking barefoot outside
Do not swim in ponds, lakes, or rivers

Available Treatments

Explore our range of treatment options for Low White Blood Cell Count: